BreakoutLabs
★ 4.8/5 · 5,117+ Verified Customers Get The Test
The biomarkers we test What's inside the kit Woman holding the test kit The Acne Root Cause Test box What's inside the kit

The Acne Root Cause Test

★★★★★ 4.8/5 · 5,117+ Verified Customers

A 12-marker at-home blood test that uncovers the hormone, blood sugar, stress, and nutrient imbalances behind your breakouts - and a personalized plan to bring your skin back to balance.

Get The Test

What if I've already tried prescriptions?
Prescriptions target the breakout - not what keeps causing them. If acne comes back after every round of treatment, the internal driver was never found. This measures the hormone, blood sugar, and stress imbalances that creams and antibiotics can't see.
What if I've been tested before and everything came back normal?
Standard labs use generic reference ranges - 'normal' isn't the same as optimal for your skin. We interpret your levels specifically for acne, where being at the edge of a range can still drive breakouts. And if your panel comes back entirely clean, our 90-day guarantee means a full refund.
Can I use this with my dermatologist?
Yes - your report includes your actual lab values, so you can bring it straight to your derm. Most acne appointments never include this panel, so it makes that visit far more productive.
What if it doesn't work for me?
You're covered by our money-back guarantee. Fewer than 1% of customers ever use it.

Built on research from

Harvard Medical School Stanford University Mayo Clinic Johns Hopkins UCSF

How it works

Step 1

Order your kit

Collect at home in ~2 minutes with a painless arm device.

Step 2

Get your results

See your results and understand what your biomarkers reveal about your skin.

Step 3

Get clear

Follow your personalized care plan

Real members. Real progress.

Visible improvements within 4–6 weeks of starting their blueprint.

Jessica G.

“I used to dread my period because I knew the jawline breakouts were coming. Now I actually feel in control.”

Jessica G.✓ Verified member
Megan B.

“Turns out my acne wasn't hormonal at all - the test showed major gut inflammation and food sensitivities that were showing up on my face. I went from hiding behind makeup to posting makeup-free selfies for the first time IN MY LIFE!”

Megan B.✓ Verified member
Nicole

“I honestly cried when I read my report. For the first time, I knew WHY my skin was breaking out - high cortisol and low vitamin D. Having answers gave me so much peace of mind, and now my skin and confidence are both improving.”

Nicole✓ Verified member · 8 weeks after testing
Jessica K.

“I spent probably $3,000 worth of skincare every year. My skin isn't perfect yet but for the first time in my adult life, I actually understand what's happening.”

Jessica K.✓ Verified member

Individual results vary. Photos are member-submitted progress photos, shared with permission.

The BreakoutLabs difference

Board-certified dermatologist reviewed

CLIA-certified lab analysis

Painless 2-minute collection

HSA/FSA eligible

90-day money-back guarantee

What we measure

12 biomarkers across four systems - analyzed in CLIA-certified labs, interpreted specifically for acne.

Breakout drivers Skin protectors Signals & baselines

Hormones

81% of cystic cases show a hormonal imbalance
Free Testosterone Drives oil production
Total Testosterone Sets hormone baseline
SHBG Buffers excess hormones
DHEA-S Fuels stress breakouts
Albumin Carries hormones

Blood Sugar

elevated levels amplify oil-production hormones
HbA1c Amplifies oil hormones

Stress & Inflammation

behind red, painful, stress-linked breakouts
Cortisol Triggers stress flare-ups
hsCRP Tracks inflammation

Nutrients & Systems

what your skin needs to heal
Vitamin D Helps skin heal
Vitamin B12 Can trigger breakouts
Ferritin Fuels skin repair
Creatinine Checks system health

A Personalized Plan Made For Your Skin, From Your Biology

Clear Skin Blueprint

Clear Skin Blueprint

Guidance from your own lab values - down to what's on your plate.

Instant reply

Ask Clara

Your dermatologist AI - trained on your results, anytime.

Why is my skin worse this week? ClaraYour cortisol ran high on your last panel - stress weeks can show up on your skin. Here's what helps…
A fresh retest every 90 days

A fresh retest every 90 days

Free - see whether your numbers, and your skin, are moving.

Replies within 24h

Ask your care team

Weekly specialist calls and real humans behind your plan.

Get The Test

Why Start With The Acne Root Cause Test?

BreakoutLabs
Typical route
Upfront cost
$149
$150–$400+
12-marker skin panel
✓ Included
✗ Rare
Skin-specific interpretation
✓ Blueprint
✗ Generic
Time to answers
~7 days
Weeks+
Progress retesting
✓ Every 90 days
✗ Rare
Support between visits
✓ Calls + Clara
✗ None

Reviewed by board-certified physicians

Dr. Akash A. Patel
“A useful tool to help determine whether hormonal imbalances may be contributing to a patient's acne.”
Dr. Akash A. Patel
Board-certified dermatologist
Dr. Mi Hye Elisa Song, MD, FAAD
“This test is designed to identify internal factors that may be contributing to acne - the ones topical routines can't see.”
Dr. Mi Hye Elisa Song, MD, FAAD
Board-certified dermatologist
Dr. Manhong Ma, MD
“A custom approach built on your own lab values is better than guessing via trial-and-error.”
Dr. Manhong Ma, MD
Board-certified dermatologist

Everything in your first month

12-marker blood testClear Skin BlueprintAsk ClaraWeekly specialist callsFree 90-day retests
$149$229Save $80 today

then $49/month · pause or cancel anytime · HSA/FSA eligible

Get The Test

✓ 90-day money-back guarantee · less than 1% ever use it

Frequently asked questions

How does billing work?
$149 today for your first kit ($229 as a one-time test). Your membership renews at $49/month. That covers your Blueprint and updates, weekly specialist calls, unlimited Clara, and a free 12-marker retest every 90 days.
Can I cancel or pause?
Yes - anytime, from your account, in about two clicks. No cancellation fees, no phone calls.
Is this FDA approved?
Diagnostic test kits aren't FDA-approved products - that category applies to drugs. Every sample is analyzed in CLIA-certified laboratories, the same certification standard used for physician-ordered bloodwork.
Do I need a prescription?
No. You can measure the internal factors associated with your breakouts without a referral or an appointment.
Does the collection hurt? Are there needles?
Collection uses a painless arm device - not a syringe, not a vein draw. Most people finish in about 2 minutes.
Why not just get bloodwork at my doctor's?
A typical acne visit rarely includes a 12-marker panel, and standard lab reports use generic ranges with no skin-specific interpretation. We run the full panel from home, interpret it for acne, and retest every 90 days.
How fast do I get results?
Kits ship within 1–2 business days. Results and your Blueprint typically arrive within 7 days of the lab receiving your sample.
What if my panel comes back completely normal?
If your panel comes back entirely clean, our 90-day money-back guarantee applies - a full refund. Fewer than 1% of customers ever use it.
Can I use HSA/FSA funds?
Yes - testing and the plan are HSA/FSA eligible, so you can pay with pre-tax dollars.
What's in your kit?
A painless arm-collection device, prepaid return shipping, and step-by-step instructions. Collection takes about 2 minutes - no visits, no vein draws.
What do you test?
12 markers across four systems: hormones (Total T, Free T, SHBG, Albumin, DHEA-S), blood sugar (HbA1c), stress & inflammation (Cortisol, hsCRP), and nutrients (Vitamin D, B12, Ferritin, Creatinine).
30Days

Money-back guarantee

No guessing. No risk. No fine print. If your panel comes back entirely clean, you get a full refund - fewer than 1% of customers ever use it.

Get The Test
$149 todaythen $49/month · cancel anytime Get The Test